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19 p, 2.4 MB |
Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations
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Temprano-Sagrera, Gerard (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sitlani, Collen M. (University of Washington) ;
Bone, William P. (University of Pennsylvania) ;
Martín Bórnez, Miguel (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Voight, Benjamin F. (University of Pennsylvania Perelman School of Medicine) ;
Morrison, Alanna C. ;
Damrauer, Scott M. ;
de Vries, Paul S. ;
Smith, Nicholas L. ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Dehghan, Abbas ;
Heath, Adam S. ;
Reiner, Alex P. ;
Johnson, Andrew ;
Richmond, Anne ;
Peters, Annette ;
van Hylckama Vlieg, Astrid ;
McKnight, Barbara ;
Psaty, Bruce M. ;
Hayward, Caroline ;
Ward-Caviness, Cavin ;
O'Donnell, Cristopher ;
Chasman, Daniel ;
Strachan, David P. ;
Tregouet, David A. ;
Mook-Kanamori, Dennis ;
Gill, Dipender ;
Thibord, Florian ;
Asselbergs, Folkert W. ;
Leebeek, Frank W. G. ;
Rosendaal, Frits R. ;
Davies, Gail ;
Homuth, Georg ;
Temprano, Gerard ;
Campbell, Harry ;
Taylor, Herman A. ;
Bressler, Jan ;
Huffman, Jennifer E. ;
Rotter, Jerome I. ;
Yao, Jie ;
Wilson, James F. ;
Bis, Joshua C. ;
Hahn, Julie M. ;
Desch, Karl C. ;
Wiggins, Kerri L. ;
Raffield, Laura M. ;
Bielak, Lawrence F. ;
Yanek, Lisa R. ;
Kleber, Marcus E. ;
Mueller, Martina ;
Kavousi, Maryam ;
Mangino, Massimo ;
Liu, Melissa ;
Brown, Michael R. ;
Conomos, Matthew P. ;
Jhun, Min-A. ;
Chen, Ming-Huei ;
de Maat, Moniek P. M. ;
Pankratz, Nathan ;
Smith, Nicholas L. ;
Peyser, Patricia A. ;
Elliot, Paul ;
Wei, Peng ;
Wild, Philipp S. ;
Morange, Pierre E. ;
van der Harst, Pim ;
Yang, Qiong ;
Le, Ngoc-Quynh ;
Marioni, Riccardo ;
Li, Ruifang ;
Damrauer, Scott M. ;
Cox, Simon R. ;
Trompet, Stella ;
Felix, Stephan B. ;
Völker, Uwe ;
Tang, Weihong ;
Koenig, Wolfgang ;
Jukema, J. Wouter ;
Guo, Xiuqing ;
Lindstrom, Sara ;
Wang, Lu ;
Smith, Erin N. ;
Gordon, William ;
van Hylckama Vlieg, Astrid ;
de Andrade, Mariza ;
Brody, Jennifer A. ;
Pattee, Jack W. ;
Haessler, Jeffrey ;
Brumpton, Ben M. ;
Suchon, Pierre ;
Chen, Ming-Huei ;
Turman, Constance ;
Germain, Marine ;
Wiggins, Kerri L. ;
MacDonald, James ;
Braekkan, Sigrid K. ;
Armasu, Sebastian M. ;
Pankratz, Nathan ;
Jackson, Rabecca D. ;
Nielsen, Jonas B. ;
Giulianini, Franco ;
Puurunen, Marja K. ;
Ibrahim, Manal ;
Heckbert, Susan R. ;
Bammler, Theo K. ;
Frazer, Kelly A. ;
McCauley, Bryan M. ;
Taylor, Kent ;
Pankow, James S. ;
Reiner, Alexander P. ;
Gabrielsen, Maiken E. ;
Deleuze, Jean-François ;
O'Donnell, Chris J. ;
Kim, Jihye ;
McKnight, Barbara ;
Kraft, Peter ;
Hansen, John-Bjarne ;
Rosendaal, Frits R. ;
Heit, John A. ;
Psaty, Bruce M. ;
Tang, Weihong ;
Kooperberg, Charles ;
Hveem, Kristian ;
Ridker, Paul M. ;
Morange, Pierre-Emmanuel ;
Johnson, Andrew D. ;
Kabrhel, Christopher ;
Trégouët, David-Alexandre ;
Smith, Nicholas L. ;
Malik, Rainer ;
Chauhan, Ganesh ;
Traylor, Matthew ;
Sargurupremraj, Muralidharan ;
Okada, Yukinori ;
Mishra, Aniket ;
Rutten-Jacobs, Loes ;
Giese, Anne-Katrin ;
van der Laan, Sander W. ;
Gretarsdottir, Solveig ;
Anderson, Christopher D. ;
Chong, Michael ;
Adams, Hieab HH. ;
Ago, Tetsuro ;
Almgren, Peter ;
Amouyel, Philippe (Institut Pasteur de Lille) ;
Ay, Hakan ;
Bartz, Traci M. ;
Benavente, Oscar R. ;
Bevan, Steve ;
Boncoraglio, Giorgio B. ;
Brown, Robert D. ;
Butterworth, Aadam S. ;
Carrera, Caty ;
Carty, Cara L. ;
Chen, Wei-Min ;
Cole, John W. ;
Correa, Adolfo ;
Cotlarciuc, Ioanna ;
Cruchaga, Carlos ;
Danesh, John ;
de Bakker, Paul I. W. ;
DeStefano, Anita L. ;
den Hoed, Marcel ;
Duan, Qing ;
Engelter, Stefan T. ;
Falcone, Guido J. ;
Gottesman, Rebecca F. ;
Grewal, Raji P. ;
Gudnason, Vilmundur ;
Gustafsson, Stefan ;
Haessler, Jeffrey ;
Harris, Tamara B. ;
Hassan, Ahamad ;
Havulinna, Aki S. ;
Heckbert, Susan R. ;
Holliday, Elizabeth G. ;
Howard, George ;
Hsu, Fang-Chi ;
Hyacinth, Hyacinth I. ;
Arfan Ikram, M. ;
Ingelsson, Erik ;
Irvin, Marguerite R. ;
Jian, Xueqiu ;
Jiménez-Conde, Jordi ;
Johnson, Julie A. ;
Jukema, J. Wouter ;
Kanai, Masahiro ;
Keene, Keith L. ;
Kissela, Brett M. ;
Kleindorfer, Dawn O. ;
Kooperberg, Charles ;
Kubo, Michiaki ;
Lange, Leslie A. ;
Langefeld, Carl D. ;
Langenberg, Claudia ;
Launer, Lenore J. ;
Lee, Jin-Moo ;
Lemmens, Robin ;
Leys, Didier ;
Lewis, Cathryn M. ;
Lin, Wei-Yu ;
Lindgren, Arne G. ;
Lorentzen, Erik ;
Magnusson, Patrik K. ;
Maguire, Jane ;
Manichaikul, Ani ;
McArdle, Patrick F. ;
Meschia, James F. ;
Mitchell, Braxton D. ;
Mosley, Thomas H. ;
Nalls, Michael A. ;
Ninomiya, Toshiharu ;
O'Donnell, Martin J. ;
Psaty, Bruce M. ;
Pulit, Sara L. ;
Rannikmäe, Kristiina ;
Reiner, Alexander P. ;
Rexrode, Kathryn M. ;
Rice, Kenneth ;
Rich, Stephen S. ;
Ridker, Paul M. ;
Rost, Natalia S. ;
Rothwell, Peter M. ;
Rotter, Jerome I. ;
Rundek, Tatjana ;
Sacco, Ralph L. ;
Sakaue, Saori ;
Sale, Michele M. ;
Salomaa, Veikko ;
Sapkota, Bishwa R. ;
Schmidt, Reinhold ;
Schmidt, Carsten O. ;
Schminke, Ulf ;
Sharma, Pankaj ;
Slowik, Agnieszka ;
Sudlow, Cathie L. M. ;
Tanislav, Christian ;
Tatlisumak, Turgut ;
Taylor, Kent D. ;
Thijs, Vincent N. S. ;
Thorleifsson, Gudmar ;
Thorsteinsdottir, Unnur ;
Tiedt, Steffen ;
Trompet, Stella ;
Tzourio, Christophe ;
van Duijn, Cornelia M. ;
Walters, Matthew ;
Wareham, Nicholas J. ;
Wassertheil-Smoller, Sylvia ;
Wilson, James G. ;
Wiggins, Kerri L. ;
Yang, Qiong ;
Yusuf, Salim ;
Amin, Najaf ;
Aparicio, Hugo S. ;
Arnett, Donna K. ;
Attia, John ;
Beiser, Alexa S. ;
Berr, Claudine ;
Buring, Julie E. ;
Bustamante, Mariana ;
Caso, Valeria ;
Cheng, Yu-Ching ;
Hoan Choi, Seung ;
Chowhan, Ayesha ;
Cullell, Natalia ;
Dartigues, Jean-François ;
Delavaran, Hossein ;
Delgado, Pilar ;
Dörr, Marcus ;
Engström, Gunnar ;
Ford, Ian ;
Gurpreet, Wander S. ;
Hamsten, Anders ;
Heitsch, Laura ;
Hozawa, Aatsushi ;
Ibanez, Laura ;
Ilinca, Andrea ;
Ingelsson, Martin ;
Iwasaki, Motoki ;
Jackson, Rebecca D. ;
Jood, Katarina ;
Jousilahti, Pekka ;
Kaffashian, Sara ;
Kalra, Lalit ;
Kamouchi, Masahiro ;
Kitazono, Takanari ;
Kjartansson, Olafur ;
Kloss, Manja ;
Koudstaal, Peter J. ;
Krupinski, Jerzy ;
Labovitz, Daniel L. ;
Laurie, Cathy C. ;
Levi, Christhoper R. ;
Li, Linxin ;
Lind, Lars ;
Lindgren, Cecilia M. ;
Lioutas, Vasileios ;
Mei Liu, Yong ;
Lopez, Oscar L. ;
Makoto, Hirata ;
Martinez-Majander, Nicolas ;
Matsuda, Koichi ;
Minegishi, Naoko ;
Montaner, Joan ;
Morris, Andrew P. ;
Muiño, Elena ;
Müller-Nurasyid, Martina ;
Norrving, Bo ;
Ogishima, Soichi ;
Parati, Eugenio A. ;
Reddy Peddareddygari, Leema ;
Pedersen, Nancy L. ;
Pera, Joanna ;
Perola, Markus ;
Pezzini, Alessandro ;
Pileggi, Silvana ;
Rabionet, Raquel ;
Riba-Llena, Iolanda ;
Ribasés, Marta ;
Romero, Jose R. ;
Roquer, Jaume ;
Rudd, Anthony G. ;
Sarin, Antti-Pekka ;
Sarju, Ralhan ;
Sarnowski, Chloe ;
Sasaki, Makoto ;
Satizabal, Claudia L. ;
Satoh, Mamoru ;
Sattar, Naveed ;
Sawada, Norie ;
Sibolt, Gerli ;
Sigurdsson, Ásgeir ;
Smith, Albert ;
Sobue, Kenji ;
Soriano-Tárraga, Carolina ;
Stanne, Tara ;
Colin Stine, O. ;
Stott, David J. ;
Strauch, Konstantin ;
Takai, Takako ;
Tanaka, Hideo ;
Tanno, Kozo ;
Teumer, Alexander ;
Tomppo, Liisa ;
Torres-Aguila, Nuria P. ;
Touze, Emmanuel ;
Tsugane, Shoichiro ;
Uitterlinden, Aandre G. ;
Valdimarsson, Einar M. ;
van der Lee, Sven J. ;
Völzke, Henry ;
Wakai, Kenji ;
Weir, David ;
Williams, Stephen R. ;
Wolfe, Charles D.A. ;
Wong, Quenna ;
Xu, Huichun ;
Yamaji, Taiki ;
Sanghera, Dharambir K. ;
Melander, Olle ;
Jern, Christina ;
Strbian, Daniel ;
Fernandez-Cadenas, Israel ;
Longstreth, W.T. ;
Rolfs, Arndt ;
Hata, Jun ;
Woo, Daniel ;
Rosand, Jonathan ;
Pare, Guillaume ;
Hopewell, Jemma C. ;
Saleheen, Danish ;
Stefansson, Kari ;
Worrall, BradfordB. ;
Kittner, Steven J. ;
Seshadri, Sudha ;
Fornage, Myriam ;
Markus, Hugh S. ;
Howson, Joana M. M. ;
Kamatani, Yoichiro ;
Debette, Stephanie ;
Dichgans, Martin ;
Universitat Autònoma de Barcelona
Multi-phenotype analysis of genetically correlated phenotypes can increase the statistical power to detect loci associated with multiple traits, leading to the discovery of novel loci. This is the first study to date to comprehensively analyze the shared genetic effects within different hemostatic traits, and between these and their associated disease outcomes. [...]
2022 -  10.1111/jth.15698
Journal of Thrombosis and Haemostasis, Vol. 20 Núm. 6 (01 2022) , p. 1331-1349
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10 p, 230.8 KB |
Direct Oral Anticoagulants or Standard Anticoagulant Therapy in Fragile Patients with Venous Thromboembolism
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López Núñez, Juan José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez Andrés, Ricard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Di Micco, Pierpaolo (Department of Internal Medicine and Emergency Room, Ospedale Buon Consiglio Fatebenefratelli, Naples, Italy) ;
Schellong, Sebastian (Department of Medical Clinic, Municipal Hospital of Dresden Friedrichstadt, Dresden, Germany) ;
Gómez-Cuervo, Covadonga (Hospital Universitario 12 de Octubre (Madrid)) ;
Sahuquillo, Joan Carles (Hospital Municipal de Badalona) ;
Ciammaichella, Maurizio (Department of Emergency Internal Medicine, Ospedale St. John, Rome, Italy) ;
Morales, Maria del Valle (Hospital del Tajo (Madrid)) ;
Bosevski, Marijan (University Cardiology Clinic, Faculty of Medicine, Skopje, Republic of Macedonia) ;
Monreal, Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Background The efficacy and safety of the direct oral anticoagulants (DOACs) in fragile patients (age ≥ 75 years and/or creatinine clearance levels ≤ 50 mL/min and/or body weight ≤ 50kg) with venous thromboembolism (VTE) has not been evaluated. [...]
2019 - 10.1055/s-0039-1683970
TH Open: Companion Journal to Thrombosis and Haemostasis, Vol. 3 (march 2019) , p. e67-e76
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14 p, 251.1 KB |
Cancer-Associated Thrombosis : Beyond Clinical Practice Guidelines-A Multidisciplinary (SEMI-SEOM-SETH) Expert Consensus
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Pachón, Vanessa (Hospital Universitario Ramón y Cajal (Madrid)) ;
Trujillo-Santos, Javier (Hospital General Universitario Santa Lucía (Cartagena, Múrcia)) ;
Domènech, Pere (Hospital Universitari de Bellvitge) ;
Gallardo, Enrique (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Font, Carme (Hospital Clínic i Provincial de Barcelona) ;
González-Porras, José Ramón (Instituto de Investigación Biomédica de Salamanca) ;
Pérez-Segura, Pedro (Hospital Clínico San Carlos (Madrid)) ;
Maestre, Ana (Hospital General Universitario de Elche) ;
Mateo, José (Institut d'Investigació Biomèdica Sant Pau) ;
Muñoz Martin, Andrés (Hospital General Universitario Gregorio Marañón) ;
Peris, María Luisa (Consorci Hospitalari Provincial de Castelló) ;
Lecumberri, Ramón (Clínica Universidad de Navarra) ;
Universitat Autònoma de Barcelona
Despite the growing interest and improved knowledge about venous thromboembolism in cancer patients in the last years, there are still many unsolved issues. Due to the limitations of the available literature, evidence-based clinical practice guidelines are not able to give solid recommendations for challenging scenarios often present in the setting of cancer-associated thrombosis (CAT). [...]
2018 - 10.1055/s-0038-1675577
TH Open: Companion Journal to Thrombosis and Haemostasis, Vol. 2 (november 2018) , p. e373-e386
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8 p, 284.1 KB |
Clinical Characteristics and Outcomes of Patients with Lung Cancer and Venous Thromboembolism
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Ruiz-Artacho, Pedro (Hospital Clínico San Carlos (Madrid)) ;
Trujillo-Santos, Javier (Hospital General Universitario Santa Lucía (Cartagena, Múrcia)) ;
López-Jiménez, Luciano (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Font, Carme (Hospital Clínic i Provincial de Barcelona) ;
Díaz-Pedroche, María del Carmen (Hospital Universitario 12 de Octubre (Madrid)) ;
Sánchez Muñoz-Torrero, Juan Francisco (Hospital San Pedro de Alcántara) ;
Peris, María Luisa (CEU Cardenal Herrera University) ;
Skride, Andris (Paul Stradins Clinical University Hospital ( Letonia)) ;
Maestre, Ana (Hospital Universitario de Vinalopó) ;
Monreal, Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Background The natural history of patients with lung cancer and venous thromboembolism (VTE) has not been consistently evaluated. Methods We used the RIETE (Registro Informatizado Enfermedad TromboEmbólica) database to assess the clinical characteristics, time course, and outcomes during anticoagulation of lung cancer patients with acute, symptomatic VTE. [...]
2018 - 10.1055/s-0038-1656542
TH Open: Companion Journal to Thrombosis and Haemostasis, Vol. 2 (june 2018) , p. e210-e217
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12 p, 182.8 KB |
Skin Autofluorescence Measurement in Subclinical Atheromatous Disease : Results from the ILERVAS Project
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Sánchez, Enric (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Betriu, Àngels (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Yeramian, Andree (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Fernández, Elvira (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Purroy, Francesc (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Sánchez-de-la-Torre, Manuel (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Pamplona, Reinald (Universitat de Lleida) ;
Miquel, Eva (Institut Català de la Salut. Centre d'Atenció Primària Borges Blanques (Lleida, Catalunya)) ;
Kerkeni, Mohsen (University of Monastir) ;
Hernández, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Simó Canonge, Rafael (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lecube, Albert (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Hernández, Marta (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Rius, Ferran (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Polanco, Dinora (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Barbé, Ferran (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Torres, Gerard (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Suárez, Guillermo (Universitat de Lleida) ;
Portero-Otin, Manuel (Universitat de Lleida) ;
Jové, Mariona (Universitat de Lleida) ;
Colàs-Campàs, Laura (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Benabdelhak, Ikram (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Farràs, Cristina (Institut Català de la Salut. Centre d'Atenció Primària Borges Blanques (Lleida, Catalunya)) ;
Ortega, Marta (Institut Català de la Salut. Centre d'Atenció Primària Borges Blanques (Lleida, Catalunya)) ;
Valdivielso, José Manuel (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Bermúdez-López, Marcelino (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Martínez-Alonso, Montse (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Universitat Autònoma de Barcelona
Aim: Advanced glycation end-products (AGEs) have been involved in the atherogenic process in the high-risk population. The goal of this study was to demonstrate that AGEs are related to subclinical atheromatous disease in subjects with low to moderate vascular risk. [...]
2019 - 10.5551/jat.47498
Journal of Atherosclerosis and Thrombosis, Vol. 26 (october 2019) , p. 879-889
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7 p, 318.6 KB |
Prothrombotic profile in patients with vasospastic or non vasospastic angina and non significant coronary stenosis
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Figueras Bellot, Jaume (Hospital Universitari Vall d'Hebron) ;
Monasterio Aspiri, Jasone (Hospital Universitari Vall d'Hebron) ;
Domingo Ribas, Enric (Hospital Universitari Vall d'Hebron) ;
Meneses Londoño, Beatriz E. (Hospital Universitari Vall d'Hebron) ;
Nieto Santa, Elsa (Hospital Universitari Vall d'Hebron) ;
Cortadellas Ángel, Josefa (Hospital Universitari Vall d'Hebron) ;
García Dorado, D.. (Hospital Universitari Vall d'Hebron)
Background: Patients with vasospastic (VA) or non vasospastic angina (NVA) without significant coronary stenosis have a reduced risk of infarction but is unclear whether or not this may be attributable to a lack of prothrombotic profile - similar to that present in patients with stable coronary artery disease (CAD). [...]
2011 - 10.1186/1477-9560-9-10
Thrombosis journal, Vol. 9, Núm. 10 (May 2011), p. 1-7
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7 p, 266.5 KB |
Use of venous thromboprophylaxis and adherence to guideline recommendations : a cross-sectional study
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Vallano, Antoni (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Arnau de Bolós, Josep M.. (Universitat Autònoma de Barcelona) ;
Permanyer i Miralda, Gaietà (Hospital Universitari Vall d'Hebron) ;
Pérez Bartolí, Jaume (Hospital Universitari Vall d'Hebron)
Background: Consensus Conferences and Guidelines for deep vein thrombosis prophylaxis have been published, which recommend the use of prophylactic heparins in patients with risk of venous thromboembolism (VTE). [...]
2004 - 10.1186/1477-9560-2-3
Thrombosis journal, Vol. 2, N. 3 (April 2004) , p. 1-7
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